Polarimeter for Research Applications
The Rudolph Research Analytical Autopol VI is designed for the most demanding analytical applications
Research grade polarimeter
Unmatched accuracy
Electronic cooling and heating from 15°-35°C
Acid resistant
Research Grade Polarimeter
The Autopol VI is designed as a research polarimeter for the most demanding analytical laboratories. If your laboratory requires the highest accuracy and must meet the most stringent compliance standards, the Autopol VI has the measurement, temperature control, communications, and data tracking capabilities your application requires.
Unmatched Accuracy: ± 0.0003° Arc
For racemic solutions and very low concentration samples, the Autopol VI laboratory polarimeter provides unmatched 4th decimal optical rotation accuracy of ±0.0003°Arc over ±1°Arc. Instrument performance for readings between -1 and 1° Arc is resolution ±0.0001, reproducibility ±0.0002 and accuracy ±0.0003.
The Autopol VI has the validation tools and features required by today’s global pharmaceutical companies, including: instrument level 21CFR Part 11 compliance, NIST traceable calibration standards. The Autopol VI is known globally for quality, accuracy and reproducibility.
Acid Resistance
The Autopol VI polarimeter comes standard with Rudolph’s Hastelloy upgrade option. This option includes a Hastelloy cell and Silco steel cell chamber for increased resistance to acids like 6 Molar HCl.
Try Before You Buy
The Autopol VI is available for a short term trial.
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AutoPol V+ and VI
Measurement
Fill Station
Laboratory Polarimeter Standard Features and Accessories
- TempTrol electronic cooling and heating from 15°-35°C
- Six standard wavelengths: 365nm, 405nm, 436nm, 546nm, 589nm and 633nm
- 21CFR11 compliance, embedded or by a separate PC
- Standard accessories: TempTrol NIST traceable quartz standard (3 rotation), TempTrol 100mm ceramic polarimeter cell, TempTrol temperature validation cell, thermoprobe and built-in sample measurement probe
Versatile Communication Capability
The Autopol VI research polarimeter’s standard communication package includes:
- Ethernet port for network cable connection
- 3 USB ports
- 2 RS 232 ports
- Facility for a USB keyboard, bar code scanner or mouse
- 32 GB non-removable compact flash data storage
- Capability to connect for remote testing and diagnostics via Internet connection
- Connect to any Windows based printer via USB or direct to the server via Windows print library
- Save measurement data direct to your network/server
TempTrol Electronic Temperature Control System
The USP <781> requires optical rotation measurements at 25°C ± .5°C (unless another temperature is specified). The (EP) European Pharmacopoeia requires optical rotation measurements made at 20° ± .5°C (unless another temperature is specified). Whatever your temperature control needs are, the Autopol VI patented TempTrol system makes your measurement in a few minutes without a water bath or any type of water circulation. The TempTrol System allows push-button temperature control of your 100mm cell, 200mm cell or Quartz Plate. Set the temperature, push “measure” and walk away. The Autopol VI polarimeter will heat or cool to a predefined temperature and then provide you with the result all in one easy step.
TempTrol heating and cooling transfer surface in the polarimeter sample chamber
Place the TempTrol cell in the Autopol VI sample chamber
TempTrol cell with mating heating and cooling transfer surface manufactured with acid resistance materials: NEDOX and Peek
Measure within ±0.2°C of the USP, EP, JP, or BP specified temperature (normally 20°C or 25°C ±0.5°C)
To Validate Temperature Performance
A temperature validation cell is provided with with every TempTrol system. The temperature validation cell along with an optional NIST traceable thermo probe is designed to validate the temperature control performance of the polarimeter and cell to ±0.2°C.
cGMP/GLP Printing
Measurement reports can be saved as an Excel or PDF file and edited quickly and easily. You can import logos and print your company’s customized “C of A” directly from the Autopol VI.
Validation and Calibration
A laboratory polarimeters operating performance should be validated regularly. The Autopol VI comes standard with the accessories, validation tool and automatic calibration functions necessary to ensure that the temperature control, temperature measurement and optical measurement processes are working accurately and reproducibly. All functions are assessed simply and conveniently through the touch screen.
Unmatched Accuracy in a Laboratory Polarimeter
For Racemic Solutions and very low concentration samples, the AUTOPOL® VI Laboratory Polarimeter provides unmatched 4th decimal Optical Rotation accuracy of ±0.0003°Arc over ±1°Arc.
Instrument performance for readings between -1 and 1° Arc is: Resolution ±0.0001, Reproducibility ± 0.0002, and Accuracy ±0.0003.
Intuitive Windows Embedded Interface
32 gigabytes of internal memory allow almost unlimited capacity for saving measurement data. The Autopol VI is network ready and data may also be saved directly to your server or to any directory desired. Internet access is possible directly from the touch screen. Windows based navigation architecture is so intuitive that most operators will never read the manual, which is stored in the internal memory. Three USB ports allow quick and easy connection to a mouse, keyboard, printer, bar code scanner, or memory stick. One USB port is located on the front of the unit and two USB ports are located on the back of the unit.
Flexible Method Management
Install your own measurement methods for immediate selection of the correct method to match your most common tests. Setting up your own custom methods is as simple as filling out a few screens.
Full 21CFR Part 11 Instrument Level Compliance
The Autopol VI 21CFR Part 11 software module is easily enabled through the user friendly touch screen. This module gives you full compliance with:
- Electronic signature
- Access levels
- Internal write protected storage
- Unique passwords
- Write protected documents sent directly to server
- Audit trail
Also available the Autopol IV, Autopol V and Autopol V Plus
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Specification
Measuring Mode: Optical Rotation Specific Rotation Specific Rotation Plus Concentration User Defined Scale Sugar Degrees °Z(ISS)
Measuring Scale: Degrees Arc, % Concentration
Measuring Range Arc Optical Rotation: ± 89.99°
Measuring Range Arc Specific Rotation: ± 999.99°
Measuring Range Concentration: 0-99.9%
Resolution: 0.0001° Arc Optical Rotation 0.0001% Concentration 0.0001° Specific Rotation
Reproducibility: 0.0002° Arc
Accuracy: 0.0003° See TB 926
Prism: Glan Thomson calcite quartz
Optical Wavelengths: 365nm, 405nm, 436nm, 546nm, 589nm, 633nm (other wavelengths available)
Wavelength Selection: Touch Screen Selectable: 6 Standard
TempTrol Range: Automatic Electronic Heating & Cooling 15°-35°C
TempTrol Accuracy: ± 0.2°C
Temperature Probe Range: 10°-100°C
Temperature Probe Accuracy: ± 0.1°C
Measurement Time: 4°/sec slewing rate & 5 sec nominal settling time
Light Source: Tungsten-halogen 6V, 20W, avg. 2,000 hr life
Sample Chamber: Accepts sample tubes up to 200mm
Data Storage: 32 GB Non-removable Compact Flash
Communication Interface: 3 USB Ports, 2 RS232 Ports, Ethernet Port for Network Connection
Calibration: Automatic calibration via touch screen
Operating System: Windows embedded
Display: 10.4 inch diagonal, 800×600 pixels, colour, flat panel monitor with resistance touch screen interface, 200 nits brightness, gasketted for spill protection
User Interface: Touchscreen
Automatic Sensitivity Control: Measures samples with transmittance as low as 0.01% (up to O.D. 4.0)
Input Power: 85-260 VAC; 48-62 Hz, 150-200 Watts consumption
Dimensions: 813mm W x 292mm H x 457mm D
Weight: 41 kg